USS Nautilus may refer to:
, a 12-gun schooner (1799–1812) , a 76-foot coast survey schooner (1838–1859) , a Narwhal-class submarine (1930–1945) , the first nuclear submarine (1954–1980)
See also Ships named Nautilus , a H-class submarine (1913–1930) called Nautilus only during construction , a 66-foot patrol/escort (1917–1919) , an O-11-class submarine (1917–1931) which carried the name Nautilus during a civilian arctic expedition in 1931 Nautilus, a cephalopod which is the namesake of these vessels