Grigorije () is a Serbian masculine given name, a variant of Greek Grēgorios (, , English: Gregory) meaning "watchful, alert". It has been used in Serbian society since the Middle Ages. It may refer to:

Grigorije the Pupil (fl. 1186), author of Miroslav Gospel Elder Grigorije (fl. 1310–1355), Serbian nobleman, Orthodox cleric and writer. Grigorije Camblak (ca. 1365–1420), Eastern Orthodox cleric and Bulgarian and Serbian writer Grigorije of Gornjak (fl. 1375–79), Serbian Orthodox monk Grigorije Račanin ( 1639), Serbian writer Grigorije Durić (1966), Serbian Orthodox bishop

See also Gligorije Grgur

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