X6 or X-6 may refer to:

Arts, entertainment, and media Mega Man X6, the sixth video game in the Mega Man X series

Electronics Nokia X6 (disambiguation), multiple touchscreen smartphones Roland Fantom X6, a synthesizer

Transportation Aircraft Airbus Helicopters X6, a proposed 19-seat twin-engined heavy lift helicopter Convair X-6, a proposed nuclear-powered aircraft Draganflyer X6, a commercial unmanned aerial vehicle

Automobiles Austin X6, a British mid-size sedan Beijing X6, a Chinese mid-size SUV Bestune X6, a Chinese compact concept SUV BMW X6, a German mid-size luxury SUV Forthing Jingyi X6, a Chinese mid-size crossover Geely Yuanjing X6, a Chinese compact SUV Landwind X6, a Chinese mid-size SUV Sehol X6, a Chinese compact SUV

Motorcycles Suzuki X6, a Japanese motorcycle

Routes X6 (New York City bus), a bus route in New York City, New York, United States

Trains LSWR X6 class, a British locomotive SJ X6, a Swedish trainset

See also 6X (disambiguation)