Egnatia can refer to:
In Greece Egnatia, Ioannina, municipality in the Ioannina regional unit Egnatia, Thessaloniki, in the Thessaloniki regional unit Via Egnatia, an ancient Roman road in Illyria, Macedonia and Thrace The A2 motorway, also known as Egnatia Odos, a modern highway in northern Greece
Elsewhere Egnatia, Byzacena, former city and bishopric in Roman Africa, now in Tunisia and a Latin titular see Egnatia, an ancient town in Apulia (Puglia, southern Italy) and former bishopric as Egnazia Appula; now Gnatia (part of Fasano), and a Latin titular see
Other Egnatia gens, an ancient Roman family KF Egnatia, a football team based in Rrogozhinë, Albania