Flacco is an Italian surname. Notable people with the surname include:

Joe Flacco (born 1985), American football player Orlando Flacco, 16th century painter from Verona Tom Flacco (born 1994), American football player Flacco, alter ego of Australian comedian Paul Livingston (born 1956)

See also Liceo Classico Quinto Orazio Flacco, the oldest secondary school in of Bari, Apulia, Italy, commonly known as the Flacco Flacco (c. 1790-1842), a chief of the Lipan Apache people, a Native American tribe Flaccus