Blood and Iron may refer to:

Blood and Iron (speech), an 1862 speech given by Otto von Bismarck American Empire: Blood and Iron, a 2001 war novel by Harry Turtledove Blood and Iron, a 2006 novel by Elizabeth Bear Blood and Iron: The Rise and Fall of the German Empire 1871–1918, a 2021 book by Katja Hoyer "Blood and Iron", a song by Bathory from Twilight of the Gods, 1991 "Blood and Iron", a song by Cirith Ungol from One Foot in Hell, 1986 "Blood and Iron", a song by Overkill from Feel the Fire, 1985 Hellboy: Blood and Iron, a 2007 animated film Blood & Iron: Bismarck's Wars for Empire, 1993 board wargame by Pacific Rim Publishing

See also Iron & Blood: Warriors of Ravenloft Blood and Steel Human iron metabolism