A nonbinding referendum was held in the Cayman Islands on 30 April 2025, alongside the general election. Voters were asked three questions.

Questions "Should the Cayman Islands develop cruise berthing infrastructure?" "Do you support the introduction of a National Lottery in the Islands?" "Do you support the decriminalisation of the consumption and possession of small amounts of cannabis?"

Campaigns The Association for Cruise Tourism (ACT), a coalition of stakeholders in the tourism industry, have led a campaign to promote the 'yes' vote on the question that, if passed, would allow the government to build cruise berthing facilities. Cruise Port Referendum (CPR) Cayman, a group advocating for environmentally-conscious tourism, has led the campaign to vote 'no'. On 11 April 2025, CPR Cayman accused the ACT in a press release of using misleading ads in their campaign. Elections Supervisor Wesley Howell responded to CPR's concerns by stating:

Results Voters rejected a proposal to build cruise ship berths, but approved the creation of a national lottery and the decriminalisation of possession of small amounts of cannabis.

QuestionForAgainstInvalid/blankTotalvotesRegisteredvotersTurnoutOutcomeVotes%Votes%Developing cruise berthing infrastructure5,41731.1511,97368.851,27518,66525,64372.79Introduction of a national lottery9,56355.177,77044.831,33018,66372.78Decriminalisation of small amounts of cannabis10,38560.406,80939.601,48318,67772.83Source: Government of the Cayman Islands

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