GDI may refer to:
Science and technology Gasoline direct injection, a type of fuel injection Graphics Device Interface, a component of Microsoft Windows Guanosine nucleotide dissociation inhibitor, a protein
Organisations Gabriel Dumont Institute, in Saskatchewan, Canada Gardner Denver, an American manufacturing company Gay Doctors Ireland, a professional organisation GDI Integrated Facility Services, a Canadian janitorial service Geena Davis Institute on Gender in Media, an American nonprofit Girl Develop It, an American educational charity Global Disinformation Index, a UK think tank Gottlieb Duttweiler Institute, a Swiss think tank Gulf Drilling International, a Qatari oil and gas company General Directorate of Intelligence, the intelligence agency and secret police of the Islamic Emirate of Afghanistan (Taliban)
Other uses Baka language (ISO 639-3 code) Gender Development Index, an index of gender equality Gordil Airport (IATA code), in the Central African Republic Gross domestic income, the total income within a state Los Guerreros del Infierno, a Mexican professional wrestling stable