Cayuga often refers to:

Cayuga people, a native tribe to North America, part of the Haudenosaunee Confederacy Cayuga language, the language of the Cayuga

Cayuga may also refer to:

Places Canada Cayuga, Ontario

United States Cayuga, Illinois Cayuga, Indiana Cayuga, Mississippi Cayuga, New York Cayuga, North Dakota Cayuga, Texas Cayuga, Oklahoma Cayuga, Wisconsin Cayuga County, New York Cayuga Island, in Niagara River Cayuga Lake, one of the Finger Lakes in New York Cayuga Lake AVA, a New York wine region Cayuga Falls, a waterfall in Ricketts Glen State Park in Pennsylvania Cayuga Park, Saint Paul, Minnesota Cayuga Terrace, a neighborhood in San Francisco, California

Other uses Cayuga duck, a breed of domestic duck Cayuga Generating Station, a coal-fired power plant in Indiana Cayuga Pictures, a film production company owned by Gardner Hunting and James H. Naulty Cayuga Productions, Rod Serling's production company, which notably produced The Twilight Zone Cayuga White, a variety of grape Cayuga (passenger train), a US passenger train operated by the New York Central Railroad and Amtrak USS Cayuga, three ships in the United States Navy HMCS Cayuga, a Tribal class destroyer with the Royal Canadian Navy SS Cayuga, one of the early steel cargo ships to ply the Great Lakes, sunk in Lake Michigan in 1895 Cayuga, a synonym of the moth genus Peoria (moth) Cayuga, a fictional New Mexican town in the movie The Vast of Night