Holthausen may refer to the following places in Germany:

in Lower Saxony

Lingen-Holthausen, a quarter of Lingen Meppen-Holthausen, a quarter of Meppen (Germany)

in North Rhine-Westphalia

Dortmund-Holthausen, a locality of Dortmund, district-free city of the Ruhr area Düsseldorf-Holthausen, a locality of Düsseldorf, district-free city of the Rhein-Ruhr-Gebiet Hagen-Holthausen, a locality of Hagen district free city Hattingen-Holthausen, a locality of Hattingen Herne-Holthausen, a locality of Herne, Germany Laer-Holthausen, a locality of Laer, in the district of Steinfurt Mülheim-Holthausen, a locality of Mülheim an der Ruhr district free city in the Ruhr area Plettenberg-Holthausen, a locality of Plettenberg Schmallenberg-Holthausen, a locality in Schmallenberg

People Ferdinand Holthausen (1860–1956), German scholar of the English and old Germanic languages Mike Holt, South African boxer of the 1950s and '60s (birth name Antione Michael Holthausen)