James O'Rourke may refer to:

Sports Jim O'Rourke (baseball) (1850–1919), American baseball player and Hall of Fame inductee Jimmy O'Rourke (baseball) (1883–1955), American baseball player, son of the Hall of Fame inductee James O'Rourke (canoeist) (1915–1983), American canoeist who competed at the 1936 Summer Olympics James O'Rourke Jr. (born 1942), his son, American sprint canoeist Jimmy O'Rourke (footballer) (1946–2022), Scottish footballer

Others Jim O'Rourke (musician) (born 1969), American musician and filmmaker Jim O'Rourke (politician), American politician