Syme may refer to:
People Arthur E. Syme (1863–1943), Australian medical doctor and racehorse owner Colin Syme (1903–1986), Australian medical administrator and innovator Connor Syme (born 1995), Scottish professional golfer Daniel Aweyue Syme, Ghanaian politician deputy government minister David Syme (1827–1908), Scottish-Australian newspaper proprietor of The Age David Syme (pianist) (born 1949), American pianist Don Syme, Australian computer scientist, creator of the F# programming language Ebenezer Syme (1826–1860), Scottish-Australian journalist, proprietor and manager of The Age Hugh Syme (GC) (1903–1965), Australian naval officer and bomb disposal operative, and employee of The Age Hugh Syme, Canadian musician and a Juno Award-winning graphic artist James Syme (1799–1870), pioneering Scottish surgeon James Thomson Syme (died 1883) co-owner Pirie Street Brewery in South Australia Jason Syme, Scottish rugby league and rugby union footballer who played in the 1990s and 2000s Jennifer Syme (1972–2001), American actress and production assistant John Syme (1795–1861), Scottish portrait-painter Julie Syme, community leader from Kaikōura, New Zealand Ronald Syme (1903–1989), New Zealand-born historian of ancient Rome and classicist William Smith Syme (1870–1928), Newfoundland-born laryngologist
Fictional characters Syme, a minor character in George Orwell's Nineteen Eighty-Four Gabriel Syme, the protagonist in G. K. Chesterton's The Man Who Was Thursday
Other uses Syme, Greece (, also romanized as Symi), a Greek island and municipality Battle of Syme Syme (mythology), a Greek mythological figure
See also SymE toxin, regulated by SymR RNA Symes, a surname Sime (disambiguation)